Hives Clinical Research Studies

Interested in joining a clinical research trial?

Hives, or urticaria are itchy red or skin-colored welts that can appear on the skin of people of all ages. These can be caused by numerous things such as an allergic reaction to a food or drug, however, experts are unsure of the exact cause of hives and urticaria. We are currently conducting a clinical research study investigating a new type of oral medication for the treatment of urticaria. Medication will be provided at no cost with no insurance needed for those who qualify, you will be reimbursed for your time and travel, and will receive care from physicians affiliated with the Clinical Research Center of Alabama.

For more information on any of the following hives clinical research studies, please contact Will O’Donnell by calling 205.209.4179 or emailing

Oral Add-On Medication Study

Age 19 – 75

Genentech CIU

The purpose of this study is to find out what effects, good or bad, GDC-0853 has on you and your CSU. GDC-0853, which is taken by mouth, is a highly selective and hinders an enzyme (protein) in the body called Bruton’s tyrosine kinase (BTK). It is being developed as a possible treatment diseases of the immune system, such as CSU

cBiologic Study-Ligelizumab versus Xolair

Age 12+

Novartis CIU

The purpose of the study is to evaluate the efficacy and safety of ligelizumab in treating adult and adolescent subjects with chronic spontaneous urticaria. Omalizumab (also called Xolair®) will be used as a comparator as this medication is the only drug in the same class as ligelizumab already approved to treat CSU patients when not adequately controlled with H1 antihistamines.

Become a Participant in our Hives Studies

If you’re interested in participating in a clinical research study at the Clinical Research Center of Alabama, call 205.209.4100 to speak with an experienced coordinator or fill out the contact form below.